Journal: International Journal of Medical Sciences
Article Title: High Expression of TBC1 Domain Family Member 22A is Related to Poor Prognosis in Ovarian Serous Cystadenocarcinoma
doi: 10.7150/ijms.99744
Figure Lengend Snippet: Differential expression of TBC1D22A. (A) TBC1D22A protein expression levels in cell lines COC1, ES-2, SKOV3, and IOSE-80. (B) Statistical analysis histogram of TBC1D22A gray value. (C) TBC1D22A mRNA expression levels in cell lines COC1, ES-2, SKOV3, and IOSE-80. (D, E) Immunohistochemical staining of TBC1D22A expression. (F) Histogram shows IHC score quantification of TBC1D22A in tumor tissues and adjacent tissues. (G) Histogram shows IHC score quantification of TBC1D22A in tumor tissues of platinum-resistant versus platinum-sensitive patients. *p < 0.05, **p < 0.01, ***p < 0.001, N.S.= not significant.
Article Snippet: The China Center for Type Culture Collection (Wuhan, China) offered the human ovarian cancer cell lines COC1, ES-2 and SKOV3, and the human normal ovarian epithelial cell line IOSE-80 was provided by the Cancer Biology Research Center at Huazhong University of Science and Technology (Wuhan, China).
Techniques: Quantitative Proteomics, Expressing, Immunohistochemical staining, Staining